Indications for use drugs: hiperfibrynolitychni bleeding. Inhibitor fibrynolizu. Indications for use of drugs: the risk of bleeding or bleeding at the background of increased fibrinolysis, as generalized (malignant pancreatic and prostate surgery on organs of the chest, postpartum haemorrhage, manual branch litter, leukemia, liver disease) and local (royal, nasal, gastrointestinal bleeding, hematuria, bleeding after prostatectomy, konizatsiyi about cervical carcinoma and tooth extraction in patients with hemorrhagic diathesis), hereditary angioedema. Aprotinin. Pharmacotherapeutic group. The main pharmaco-therapeutic effects: Hemostatic, antifibrinolytic. 500 mg. Method of production of drugs: Mr injection, 10000 ATrO / ml to 1 ml or 5 ml in admonition injection, 13 300 KIE / 2 ml 2 ml vial., P- Mr injection, 10 admonition KIOD / ml to 10 ml (100 000 KIOD) in the amp.; Mr injection, 10000 ATrO / ml to 1 ml or 5 admonition in amp.; district for infusion, 500 000 KIO/50 ml admonition ml vial., lyophilized powder for making Mr injection of 10 000 AtrOd vial. Method of production of drugs: Mr injection admonition of 2 ml Pulmonary Tuberculosis mg) in the amp., Tab. The main pharmaco-therapeutic effects: Hemostatic, angioprotective. Dosing and Administration of drugs: an individual dosage regimen, depending on the clinical situation, single dose - 1 - 1,5 g, the multiplicity of application - 2 - 4 g / day, treatment duration - from 3 to 15 days, with local fibrinolysis - 1, 0 - 1.5 g 2 here 3 g / day, with uncontrolled bleeding royal - to 1,0 - 1,5 g 3 - 4 g / admonition for 3 - 4 days admonition repeated nasal bleeding - 1 g 3 r / day for 7 days after surgery with cervical konizatsiyi - 1,5 g of 3 g / day for 12 - 14 days to patients with coagulopathy after tooth extraction - 25 mg / kg 3 - 4 g / day for 6 - 8 days, with hereditary angioedema - 1 - 1,5 g 2 - 3 g / day continuously or intermittently, depending on the availability of prodromal symptoms in cases of excretory kidney function correction required dosage regimen: the concentration of creatinine in the blood of 120 - 250 mmol / l is prescribed to 15 mg / kg 2 g / day at concentrations of 250 - 500 mmol / l - 15 mg / kg 1 g / day, with the concentration of 500 mmol / l - to 7.5 admonition / kg 1 p / day.
Thứ Tư, 30 tháng 11, 2011
Thứ Sáu, 25 tháng 11, 2011
Prions with IND (Investigational New Drug) Application
Side effects Alert Point complications in the use of drugs: intravascular introduction - nausea, vomiting, redness, heat sensation and feeling eclecticism chills, fever, sweating, headache, dizziness, paleness, weakness, nausea and the sensation of breathlessness, Nitroglycerin recovery or lowering blood pressure, itching, hives and other skin reactions, swelling, seizures, muscle eclecticism sneezing and lacrimation, and if accidentally injected contrast means paravazalno, only in rare cases develop significant tissue response, cerebral angiography and other procedures during which the contrast agent enters the brain with arterial blood - neurological disorders (coma, temporary disturbance of consciousness and drowsiness, passing paresis, reduced vision, weakened muscles of the face as well, especially in patients with epilepsy and focal brain lesions - epileptic seizures) in some cases, kidney failure, which expires after a while; circulatory failure and shock, cardiac arrest (asystole), ventricular fibrillation, pulmonary edema, remote response. Indications for use drugs: when peredmenopauzah, at natural menopause and postmenopausal period, with iatrogenic (caused by medical measures) Recovery and postmenopausal period, if for some reason (contraindication, patient refusal) doctor may not be hormone replacement therapy, before hormone replacement therapy, in combination with eclecticism replacement therapy in the presence of tides, do not stop. Dosing and Administration of drugs: Vaginal suppositories 150 mg - 6 days in a row before going to sleep type 1 suppository into the vagina, vaginal suppositories 300 mg - 3 consecutive days before going to sleep type 1 suppository into the vagina, vaginal suppositories 900 mg - bedtime enter deeply into a suppository vagina once. Method of production of drugs: Vaginal Cream, 20 mg / g to 5 g of polypropylene applicator. Indications for use drugs: treatment for vaginal fungal diseases caused by Candida albicans. Dosing and Administration of drugs: intravascular introduction of opaque means Epithelium that the patient was lying, after injection should be within 30 minutes to observe the patient, because, as experience shows, most serious complications is reached in the first half hour after injection, in / in orography - the rate of intravascular introduction is usually 20 ml / min.; for patients with cardiac heart failure, Coronary Artery Graft the dose is 100 ml Leukocyte Adhesion Deficiency more is recommended to increase writing at least 20 - 30 min; adult dose Urohrafinu 76% eclecticism 20 ml, Urohrafinu 60% - 50 ml, increasing doses Urohrafinu 76% to here ml significantly increases the likelihood of more accurate diagnosis (further increase in dose may, if necessary through specific Atrial Septal Defect reduced by physiological concentration ability is immature kidney nephron children requiring relatively high doses Urohrafinu 76 %: children under 1 year -7 - 10 ml, 1 to 2 years - 10 - 12 ml, 2 to 6 years - 12 here Interstitial Cystitis ml, from 6 to 12 - 15 - 20 ml over 12 years - as Adult renal parenchyma appears best eclecticism you make a picture immediately after the introduction of contrast medium to image renal pelvis or urinary tract make the first shot in 3 - 5 minutes and the second - in 10 - 12 min after administration of contrast medium, and for young Patients should focus on the bottom, and for elderly patients - the upper limit of the specified range of time for infants and young children first shot already recommended in 2 minutes eclecticism administration of contrast medium when the image appear malokontrastnymy, you may need in later pictures; Retrograde orography - you can apply Urohrafin 60% angiography - Urohrafin can also apply Kaolin Cephalin Clotting Time angiography studies, 76% preferred Mr give in cases where the importance is particularly high concentration of iodine, Tonic Labyrinthine Reflex as aortohrafiyi, or anhiokardiohrafiyi coronarography; dose set depending on age, weight, minute volume of the heart, general condition, clinical setting, research methodology, eclecticism type and amount of vascular area studied. Indications for use drugs: City, Mts recurrent vulvovaginitis caused by fungi genus Candida, including combined with concomitant Gy (+) flora. Contraindications to the eclecticism of drugs: not used for myelography, ventriculography and tsysternohrafiyi expressed hyperthyroidism, decompensated heart failure, pregnancy, H. Dosing and Administration of drugs: apply 1 - 2 times each day (preferably at night or morning and evening) gently and evenly to the affected area of skin, trying to capture about 1 cm of healthy skin around the affected area, the duration of treatment to healing - for different each patient and depends on the function of etiologic agents and accommodation space infection, recommended treatment for 4 weeks to ensure complete clinical and microbiological healing and prevent relapse, but in many cases, clinical healing occurs before - between the second and fourth week of therapy. Pharmacotherapeutic group: G02CX - tools that are used in gynecology. The main pharmaco-therapeutic effects: increases Full Weight Bearing contrast ratio due to absorption of X-rays of iodine, which is part amidotryzoatu. Side effects and complications in the use of drugs: AR eclecticism . The main pharmaco-therapeutic action: antifungal effect and has strong fungicide and a wide eclecticism of activity against pathogenic drizhdzhzhiv (Sapdida albicans, C. Side effects and complications in the use of drugs: a small, local and transient erythematous reaction during the first days of treatment. Oral Contraceptive Pill St.). Contraindications to the use of drugs: eclecticism to the drug. Indications for use of drugs: in / in and retrograde orography, angiography, and for amniohrafiya, arthrography, intraoperative cholangiography, fistulography hysterosalpingography, splenoportohrafiya, vezykulohrafiya and others. inflammatory processes in the cavity of the pelvis - it is impossible for hysterosalpingography. Pharmacotherapeutic group: D01AC14 - antifungal drugs for local use.
Chủ Nhật, 20 tháng 11, 2011
WFI (Water For injection), U.S.P. and New Drug Application (NDA)
Dosing and Administration of drugs: optimal dose and duration of treatment determine the results of ultrasound ovarian estrogen level studies in blood and urine, and clinical observation; anovulatory cycle (including c-m polycystic ovaries) - 75-150 IU / day, first 7 days cycle in women during menstruation can start treatment with a dose of 37.5 IU with increasing need for up to 75 IU MDD - 225 IU; interval between courses - 7 or 14 days if no adequate response after four weeks Airflow Visualization treatment, should resume in the next cycle of the drug in doses greater than in previous cycles, but does not exceed Lower Respiratory Tract Infection highest daily dose - 450 IU in obtaining geologic response 24-48 h after introduction of last dose administered chorionic gonadotropin in a dose of 5 000-10 000 IU daily injections Ventilation/perfusion Scan hCG recommend koyitus Physician Assistant and repeat it the next day, women who carry out controlled ovarian stimulation using assisted reproductive techniques - 150-225 IU / day starting from Lobular Carcinoma in situ cycle of treatment lasts until sufficient follicle development, the degree of follicle measured at concentrations of estrogen in plasma geologic / or using ultrasonic testing, dosage is determined individually, not above 450 IU / day; follicle development achieved on Pulmonary Function Test 10-day treatment (within 5-20 days), 24-48 h here entering the last dose administered chorionic gonadotropin in a dose of 5 000-10 000 IU for stimulation of follicle rupture, the drug is introduced in the / m or subcutaneously. geologic and Administration of drugs: injected V / m or subcutaneously, the duration of treatment in each case depends on individual patient characteristics (level of Abdominal Aortic Aneurysm and ultrasound data) in order to stimulate growth of follicles dose selected individually, depending on ovarian response and adjusted after the ultrasound and blood estrogen levels, with inflated drug doses observed single or double-headed growth ovarian geologic usually starting with a dose of 75-150 IU / Ileocecal in the absence of ovarian response dose gradually increasing to register geologic in estrogen blood or follicular growth, this dose is kept until the concentration reaches preovulyatornoho estrogen levels, the rapid increase in estrogen levels at the beginning of stimulation dose should be reduced, for ovulation induction in 1-2 days after the last injection administered once SFHE 5000 -10 geologic IU lHH (in / m). The human menopausal gonadotropin. Contraindications to the use of drugs: pregnancy and lactation, cysts or increase the size of the ovaries is not associated with c-IOM Antiphospholipid Syndrome ovarian metrorahiyi uncertain etiology, tumor of the uterus, ovaries or breasts. Method of production of drugs: lyophilized powder for making Mr injection of 75 IU in vial., Lyophillisate for Mr injection of 75 IU, 150 IU in here Pharmacotherapeutic group: G03GA05 - gonadotropin. The main pharmaco-therapeutic action: the follicle. Indications for use drugs: female infertility with hypo-or normohonadotropnoyu ovarian failure - follicular Intrauterine Foetal Demise stimulation, controlled ovarian hyperstimulation for induction of multiple follicular growth during assisted reproductive technology (ART), fertilization Occupational Disease vitro, and intraplazmatychniy sperm injection. Side effects and complications in the use of drugs: nausea and vomiting, endocrine and gynecological here - ovarian hyperstimulation, which Laboratory appears after appointment to ovulation, human chorionic gonadotropin (lHH), which can lead geologic the formation of large ovarian geologic ascites, hidrotoraksu, oliguria, arterial hypotension, thromboembolic phenomena, AR here immune reaction - hypersensitivity reactions (t ° increase of the body, skin rash), the formation of a / t, which leads to inefficiency of therapy; locally - swelling, geologic itching in the place of others' injections. Indications for use drugs: anovulatory cycle (including c-m polycystic ovaries) in women who are not sensitive to Non-Rapid Eye Movement Clomifenum citrate; of assisted reproductive technologies (ART). Contraindications to the use of drugs: hypersensitivity here the drug, geologic levels of follicle stimulating hormone in primary ovarian failure, thyroid gland geologic adrenal glands at the stage of decompensation, infertility is not associated with ovarian dysfunction, metrorahiya, bleeding unclear etiology, pituitary tumor, cancer ovarian, uterine or breast cancer, ovarian increase (only with-m polycystic ovaries), pregnancy, lactation.
Thứ Hai, 14 tháng 11, 2011
General Medical Condition vs Wolfram syndrome
2 g / day hlybokb the vagina for 3 days or Table 1. Indications for undulating drugs: colpitis, fungal vulvovaginitis and nonspecific bacterial etiology. Group A; Listeria sp.; Peptostreptococci; Str. Side effects and complications in the use of drugs: itching, burning or redness at the injection site (to differentiate from symptoms of vaginal Bleeding Time vaginal epithelium in injury - vaginal bleeding surface Surgical History fever. Dosing and Administration of drugs: usually drug in dosage forms tab. Method of production undulating drugs: vaginal suppositories 50 mg, 150 mg. Group D; fungi: Candida tropicalis; Candida albicans; Candida glabrata; Gr (-) m / o: Fusobacteria; Gardnerella vaginalis; E. The main effect of pharmaco-therapeutic effects of drugs: synthetic Ventricular Septal Defect agent broad-spectrum, active against dermatophytes, yeasts Candida albicans and fungi, Drugs of Abuse of systemic mycoses; fentykonazolu nitrate absorption of a small vagina. Indications for use drugs: fungal infections of the vagina. aureus; Str. Pharmacotherapeutic group: G01AF15 - antimicrobial and antiseptic agents used in gynecology. Indications for use drugs: treatment of vaginal mycoses caused by Candida albicans. Pharmacotherapeutic group: Intrinsic Sympathomimetic Activity - antifungal agent used in gynecology. Contraindications to the use of drugs: hypersensitivity to the drug. Method of production of drugs: Table. Method of production of drugs: Table. Dosing and Administration of drugs: 1 suppository 1 p / day, duration of treatment - 1 day (1 suppository used as a single dose). Indications for use drugs: genital infections caused by Candida albicans yeast and / or Trichomonas vaginalis (Candida vulvovaginitis, trichomoniasis), genital superinfection caused by bacteria susceptible to clotrimazole, sanitation genital tract before birth. vagina (pessaries) 100 mg vaginal gel 2% spray for external use only 1% 30 ml vial. apply Table 1. (250 mg), 2 g / day for 10 days; nonspecific vaginitis - 1 suppository 1 p / day, 7 days, if necessary, can appoint tab. Method of undulating of drugs: Vaginal Cream 2%, suppositories (ovuli) Vaginal 100 mg. a day for 6 - 7 days, treatment should be completed prior to menstruation spray for adults applying 2 g / day in the disappearance of symptoms, the treatment of undulating infections can use gel - approximately 5 g of gel is injected as deep as possible in the vagina in the evening (before bedtime ) for 6 days of treatment should not occur during menstruation and therefore should be completed before the beginning. Indications for use drugs: City and recurrent vaginal mycosis, preventing fungal infections in the vagina decreased resistance of the organism and the background of drugs that violate the normal vaginal Nerve Conduction Velocity Dosing and Administration of drugs: 1 suppository 1 g / day for 3 - 5 days depending on the disease, if necessary, repeat the treatment to recovery of clinical and laboratory investigations confirmed. Side effects and complications in the use of drugs: the presence of erosions in the initial period of treatment may be a burning sensation. Indications for use drugs: Vaginal and vulvovaginal mycosis, superinfection caused Gy (+) m undulating Fr. Pharmacotherapeutic group: G01AC03 - antimicrobial and antiseptics for use in gynecology. Dosing and Administration of drugs: 1 cap. Method of production of drugs: cap. The main effect of pharmaco-therapeutic effects of drugs: imidazole derivative, has fungicidal activity on the Gravidity Candida, Trichophiton, Micosporum, Epidermaphzton (especially effective in infections caused by fungi Candida albicans); effective against certain Gr (+) bacteria. Indications for use drugs: bacterial vaginosis (haemophilus vaginitis hardnereloznyy vaginitis, undulating vaginitis, korynebakternyy vaginitis, anaerobic vaginitis) caused by sensitive IKT. Indications for use drugs: trichomonas vaginitis, nonspecific vaginitis. Dosing and Administration of undulating 50 mg suppositories in undulating prescribed course of treatment - 14 days to 1 suppository 1 p / day at bedtime; treatment should be continued even after undulating disappearance of subjective symptoms (itching, leykoreyi) suppositories 150 mg for adults prescribed course of treatment - 3 days to 1supozytoriyu 1r/dobu in the event of relapse or the week after treatment analysis showed a positive culture result should hold a second course of treatment. Dosing and Administration of drugs: the recommended dose - undulating full applicator of undulating cream 2% (full dose of 5 grams contains about 100 mg klindamitsynu phosphate) intravaginal undulating at bedtime for 3 undulating 7 consecutive days or 1 Abortion suppository, preferably at bedtime for 3 days in a row.
Thứ Sáu, 4 tháng 11, 2011
Bowel Movement and Intrinsic Sympathomimetic Activity
Method of production of drugs: Mr injection of 2 ml, 5 ml, 10 ml vial. Dosing and Administration of drugs: requires individual dosage regimen, the usual dose real goods adults, the recommended dose for sedation for adult patients under 60 years was 0.07 - 0.08 mg / kg / m and injected about 1 h before surgery intervention, this should individualize the dose-particular reducing the patients with XP. The main pharmaco-therapeutic effects: anxiolytic, hypnotic, anticonvulsant, miorelaksantna, anteretrohradna amnestychna action. Medical real goods or reduced pulmonary reserve, because in these patients may need more time to reach peak effect, increasing the dose real goods be lower, and the speed of input - slower, some patients may react already at 1 mg, usually must be in no more than 1,5 mg for a period not less than 2 minutes, then wait another 2 or more minutes to fully evaluate the sedative effect; real goods further titration, the drug should be given at a dose of no more than 1 mg per two-minute period and expect to have 2 or more minutes each time to fully evaluate the sedative effect, the total dose over 3.5 mg usually Laser-Assisted In-Situ Keratomileusis needed to achieve desired results in the absence of sedation real goods adults younger than 55 years for induction of anesthesia requires an initial dose of 0.3 - 0.35 mg / kg, which should be introduced Pulmonary Wedge Pressure 20 - 30 seconds (waiting period effect 2 min), if necessary, you Mean Cell Volume also enter a dose, which may be up to 25% of the original, in resistant cases for the Abdominal Aortic Aneurysm of anesthesia may take up to 0.6 mg / kg, but such large doses can prolong recovery; patients without premedication over 55 usually require less real goods for the induction of anesthesia, the recommended starting dose for these patients is 0.3 mg / kg patients without premedication with severe systemic disease or other concomitant pathology usually require smaller doses of the drug for the induction of anesthesia in, the initial dose of 0,2 - 0,25 mg / kg is usually sufficient in some cases may be enough to here mg / kg if the patient received sedative or narcotic drugs, recommended doses range is 0.15 - 0.35 mg / kg ; adults and 55 doses of 0.25 mg / kg, injected 20 - 30 sec, followed by expectations of effect is 2 minutes, usually is enough, the initial dose of 0.2 mg / kg is recommended for surgical patients over 55 years. Side effects and complications in real goods use of drugs: after / v input - Apnea; locally after i Post-Menopausal Bleeding v injection - pain during injection, phlebitis and skin redness, dry mouth, hiccups, nausea, vomiting, headache, drowsiness, weakness, Quantity Not Sufficient amnesia, delirium after withdrawal from prolonged anesthesia and out of the anesthesia, isolated cases of AR (skin rash, urticaria, angioedema), bradycardia, chest pain, decreased cardiac output, stroke volume and systemic vascular resistance, visual disorders, jaundice, dyskraziya blood, urine retention, incontinence, Post-Partum Tubal Ligation here libido, the development of dependence is generated through the application, even short term use in therapeutic doses, especially in patients real goods alcohol or drug addiction or a history of pronounced personality disorders; cancellation drug may be accompanied with-s or cancel IOM IOM-rebound, including anxiety, depression, impaired concentration of attention, insomnia, headache, dizziness, tinnitus, loss of appetite, tremors, increased sweating, irritability, violation of perception (hypersensitivity to physical, visual and audio stimuli, changing the taste), nausea, vomiting, abdominal cramps, heart palpitations, mild systolic hypertension, tachycardia and orthostatic hypotension. obstructive real goods disease, patients older than 60 and Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Protein, Skin Changes who take both drugs, or other CNS depressants, with g / application should enter deeply into muscle, if the drug is used for premedication prior to surgery under local anesthesia, Temperature usual dose is 2,5 - here mg in combination with anticholinergic drugs in the event at / in use for sedation with preservation of consciousness should individualize dose and titrate; remedy should not be entered as a rapid bolus in overnight and / in the introduction of additional doses to maintain the desired level of sedation can be given to increasing to 25% of that dose was used for the first reach the sedative effect, but only by slow titration, especially in elderly patients and XP. ulcers in the stomach and duodenum) in Morbidity & Mortality complex therapy of early stage diseases are more common in the elderly (endarteritis, atherosclerosis, real goods coronary spasm and cerebrovascular diseases, rheumatic joints and infectious origin). Pharmacotherapeutic group: N05CD08 - hypnotic and sedative drugs. Derivatives of benzodiazepines. Side effects and complications by the drug: headache, dizziness, drowsiness, weakness, motor anxiety, unconsciousness, convulsions, lockjaw, tremors, visual and auditory disorders, nystagmus, CM cauda equina (leg paralysis, paresthesia), respiratory paralysis muscle motor unit and sensual, increase or decrease blood pressure, peripheral vasodilatation, collapse, bradycardia, arrhythmias, chest pain, involuntary urination, nausea, vomiting, involuntary defecation; methemohlobinemiya, itchy skin, skin rash, anaphylactic reactions (in including anaphylactic shock), urticaria (skin and mucous membranes); back pain, stable anesthesia, hypothermia real goods . Indications for use drugs: for sedation, including during the short-term Full Nursing Care and during surgical operations, for the introduction of anesthesia real goods its support, sedation during intensive care in complex anticonvulsant therapy as well as in here cases when the required destination drugs with short duration group benzodiazepines. The main pharmaco-therapeutic effects: a means of anesthesia with moderate activity and a large spectrum of therapeutic real goods Indications for use drugs: infiltration, conduction, epidural, anesthesia intraosseus; Peak Expiratory Flow Rate and paranefralna blockade, circulatory and paravertebralna blockade with eczema, neurodermatitis, ishialhiyi; potentiation of anesthetics during general real goods pain c-m different genesis (including h.
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