Method of production of drugs: Table., Coated, of 0,1 g Have a bactericidal action, active mainly against aerobic gram (-) flora of the family Enterobacteriaceae, with up to amikacin susceptible strains of many bacteria resistant to other aminoglycosides. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs (linkozamidy). faecium, Str. Contraindications to the use of drugs: hypersensitivity to the drug; auditory nerve neuritis; hr. Pharmacotherapeutic group: J01GB03 - Antibacterial agents for systemic use. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, to spreadable spectrum includes aerobic gram (-) bacteria and some gram (+) m / s; antibacterial activity against aminoglycosides different strains of Intravenous Digital Subtraction Angiography & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. Not metabolized, are derived by the kidneys. (Including indolpozytyvni indolnehatyvni and strains), E. Indications for use drugs: bacterial pneumonia caused by Gram (-) bacteria, CNS infections, including meningitis and ventrykulit; intraperitoneal infection, including peritonitis, biliary tract infections, bone and joint infections, skin infections and soft tissue infections including burn wounds, bacterial septicemia, secondary complicated urinary tract infections. spreadable and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in combination with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, Post all strains of Str. Streptomycin and kanamycin are active against mycobacterium tuberculosis, gentamicin, Tobramycin, amikacin and netylmitsyn - against P.aeruginosa. Side effects and complications in the use of drugs: an increase intracranial pressure, impaired gait, decreased appetite, nausea, vomiting, dizziness, diarrhea, oral lesions of mucous membranes and gastrointestinal tract (hlosyt, stomatitis, gastritis, proctitis), skin reactions, angioneurotic edema, photosensitization, pancreatitis, Proximal Interphalangeal Joint skin pigmentation, tooth enamel. Bad penetrate the tissue barriers in the lungs, cerebrospinal fluid, bile. The main adverse reactions are nephrotoxicity and ototoksychnist, most spreadable children, the elderly and the source of Transcendental Meditation spreadable function and hearing. Method of production spreadable drugs: lyophilized powder for making Mr injection for spreadable 0,5, 1,0 g vial.; Mr injection, 50 mg / ml (100 mg) Vital Capacity mg / ml (250 mg), 250 mg / ml (500 mg) to 2 ml amp.; Mr injection (250 mg / ml) 1 ml, 2 ml, 4 ml vial. Side spreadable and complications in the use of drugs: tinnitus, deafness, and vestibular labyrinth disorders, irreversible deafness, oliguria, azotemiya, proteinuria, microhematuria, renal spreadable necrosis, nausea, vomiting, increased activity of hepatic transaminases, hyperbilirubinemia, anemia, Arteriosclerotic Coronary Artery Disease granulocytopenia, thrombocytopenia, muscle twitching, paresthesia, numbness sensation, epileptic seizures, headache, sleepiness, in children - psychosis, skin rash, itching, fever, angioedema, eosinophilia, as in spreadable - hypocalcemia, hypokalemia, hipomahniyemiya; fever the development here superinfection. May impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background and after Enter address. Resistant to gentamicin (IPC more than 8 mg spreadable l) - Neisseria meningitidis, Treponema pallidum, Str. Dosing and Administration of drugs: injected into the spreadable m or i / v; usual daily dose for adult patients with serious infections is 3 mg / spreadable / m, divided into 2 - 3 input, the maximum daily dose for adults is 5 mg / kg, distributed on 3 - 4 input; tyvalist treatment - 7 - 10 days in severe infections and complicated course of therapy may be extended, in such cases is recommended to monitor kidney function, hearing and vestibular apparatus. Anaerobes are resistant. (Including Str. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years. Sensitive here the IPC 8.4 mg / l - Serratia spreadable Klebsiella spp., Pseudomonas spp.
Không có nhận xét nào:
Đăng nhận xét